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Caltech

Howard & Jan Oringer Seminar

Tuesday, May 10, 2016
12:00pm to 1:00pm
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Annenberg 105
Computational Biology in Translational Cancer Research
Xiaole Shirley Liu, Professor, Biostatistics and Computational Biology, Harvard School of Public Health,

Computational biology is playing important roles in precision cancer therapy.  I will discuss our efforts using computational biology to mine high throughput sequencing data in order to aid translational cancer research.  Specifically I will discuss three areas of our current foci: using public ChIP-seq data to understand cancer gene regulation, using CRISPR screen data to identify tumor vulnerabilities and targeted combination therapy, and using RNA-seq data to model tumor infiltrating Xiaole Shirleyimmune cells and T-cell repertoires.

For more information, please contact Diane Goodfellow by phone at 626-395-6842 or by email at [email protected].