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Organic Chemistry Seminar

Wednesday, May 24, 2023
4:00pm to 5:00pm
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Gates Annex B122
Polymer Chemistry-Inspired Approaches to Precision Biomacromolecules
Jia Niu, Assistant Professor, Department of Chemistry, Boston College,

Despite recent progress in genomics, proteomics, and glycomics, the structural heterogeneity of biomacromolecules such as polysaccharides and proteins remains a significant barrier for their characterization and utilization. A long-term goal of our research group is to develop synthetic approaches to precision biomacromolecules and their mimetics and use them to understand and manipulate biology. In this seminar, I will discuss two polymer chemistry-inspired approaches to precision biomacromolecules: (1) A SuFEx-based approach to peptides, proteins, and glycomimetic oligomers with defined sites, sequences, and stoichiometry of sulfation; (2) chemical synthesis of polysaccharides from living polymerization.

For more information, please contact Annette Luymes by phone at x6016 or by email at [email protected].