Behavioral Social Neuroscience Seminar
Despite tremendous recent progress in elucidating core neurocomputational components that underlie economic decision-making, we still know little about the mechanisms that coordinate the various signals within and across various brain regions. I will discuss results from recent electrocorticography (ECoG) studies suggesting a fundamental role of neural oscillations in governing intra- and inter-regional communication during decision-making. Specifically, we recorded local field potentials in the prefrontal cortex of in neurosurgical patients who were engaged in a gambling task. ECoG signals reflect the coordinated activity of ensembles of hundreds of thousands of neurons, and are uniquely poised to reveal fast, circuit-level computations in the human brain. We found that different aspects of the gambling game generated event-related changes in oscillatory activity across multiple areas and frequency bands. Furthermore, oscillatory interactions between lateral and orbital prefrontal regions support cognitive processes underlying decision-making under uncertainty. Together, these data highlight the importance of network dynamics in characterizing neural basis of economic decision-making.