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BBE/Moore Scholar Seminar- Vamsi Mootha | Tuesday, January 9, 2024 at noon

Tuesday, January 9, 2024
12:00pm to 1:00pm
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BBE/Moore Scholar Seminar

Speaker: Vamsi Mootha, Professor

Systems Biology and Medicine

Harvard Medical School

Date: January 9, 2023

Reception: 11:30 am

Time: 12 pm

Location: Broad 100

Talk Title: Mitochondria, oxygen, and human disease

Abstract: A decline in mitochondrial number and activity are associated with a spectrum of human conditions – from rare, inborn errors of metabolism to neurodegeneration and aging. In humans the organelle is encoded by two genomes: a small, high copy number genome (mtDNA) that is maternally transmitted, and the diploid nuclear genome inherited from both parents. In this talk, I will present our lab's latest efforts employing biobank-scale genomics to understand the genetic basis for cross-talk between these genomes. Then I will discuss our lab's recent efforts to harness hypoxia – or low ambient oxygen – as a therapy for mitochondrial disease.

For more information, please contact Tish Cheek by phone at 626-395-4952 or by email at [email protected].