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Organic Chemistry Seminar

Friday, August 23, 2019
4:00pm to 5:00pm
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Noyes 153 (J. Holmes Sturdivant Lecture Hall)
Late-Stage Functionalizations
Dr. Tobias Ritter, Managing Director, Max-Planck-Institut für Kohlenforschung,

Late-stage functionalization reactions should reliably functionalize already complex molecules to quickly access value-added molecular diversity. Late-stage functionalization is desirable in many areas of discovery such as in drug or agrochemical development and a requirement in other areas such as the synthesis of positron-emission tomography (PET) tracers. I will describe the development of novel, modern highly selective reactions in late-stage functionalization, as well as their application in transition-metal-catalyzed and photoredox reactions, with a focus on the synthesis of 18F and 19F containing complex small molecules. In particular, I will describe the development of a broadly useful new C-H functionalization reaction to create molecular complexity for applications in catalysis, drug discovery, and medicine.

For more information, please contact Annette Luymes by phone at 626-395-6016 or by email at aluymes@caltech.edu.