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Organic Chemistry Seminar

Wednesday, February 26, 2020
4:00pm to 5:00pm
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Noyes 153 (J. Holmes Sturdivant Lecture Hall)
C-H and C-O Functionalization via Radical Chaperones
David A. Nagib, Assistant Professor, Department of Chemistry and Biochemistry, Ohio State University,

Our research is focused on harnessing the untapped reactivity of abundant chemical feedstocks to enable late-stage functionalization of medicinally relevant molecules. We have recently developed new approaches for selective C-H and C-O functionalization of alcohols, amines, and carbonyls, using a combination of radical (1e-) and closed shell (2e-) processes that act in concert with one another. These radical chaperone strategies have enabled discovery of new classes of reactivity to streamline the synthesis of complex molecules with biological and industrial significance.

For more information, please contact Annette Luymes by phone at 626-395-6016 or by email at aluymes@caltech.edu.