Medical Engineering Distinguished Seminar: Steven Jacques
Optically detecting abnormalities in biological tissues can find both constitutional changes seen with absorption, fluorescence and Raman signals, and structural changes based on the light-scattering properties of the tissue. This seminar discusses the use of light scattering to detect structural changes. Both local microscopic measurements and large-scale macroscopic measurements can characterize the sub-micron scale of structure in cells and tissues. Changes in hydration can alter light scattering, changes in collagen content and organization can alter light scattering. Light scattering is a useful contrast parameter for imaging structural changes in tissues, and can characterize the character of the structural changes.
Steven L. Jacques received a B.S. degree in Biology at M.I.T., and an M.S. degree in Electrical Engineering and Computer Science and a Ph.D. degree in Biophysics and Medical Physics from the University of California-Berkeley. In 1983, he joined the Wellman Laboratory for Photomedicine at MGH, becoming a Lecturer in Dermatology/Bioengineering, Harvard Medical School. In 1988, he joined the University of Texas M. D. Anderson Cancer as Assistant Professor of Urology/Biophysics, and later as tenured Assoc. Professor. In 1996-2017, he served as Professor of Biomedical Engineering & Dermatology at Oregon Health & Science University. After two years at Tufts University in Boston, he is now an Affiliate Professor of Bioengineering at the University of Washington in Seattle. https://omlc.org/