Developing Our Sense of Smell

When our noses pick up a scent, whether the aroma of a sweet rose or the sweat of a stranger at the gym, two types of sensory neurons are at work in sensing that odor or pheromone. These sensory neurons are particularly interesting because they are the only neurons in our bodies that regenerate throughout adult life—as some of our olfactory neurons die, they are soon replaced by newborns. Just where those neurons come from in the first place has long perplexed developmental biologists. Previous hypotheses about the origin of these olfactory nerve cells have given credit to embryonic cells that develop into skin or into the central nervous system, where ear and eye sensory neurons, respectively, are known to originate. But biologists at the California Institute of Technology (Caltech) have now found that neural-crest stem cells—multipotent, migratory cells unique to vertebrates that give rise to many structures in the body such as facial bones and smooth muscle—also play a key role in building olfactory sensory neurons in the nose.

Two Decades of Discoveries

Although Keith Matthews was about to make history, he went about his tasks like any others. It was the night of March 16, 1993, nearly 14,000 feet above sea level on Mauna Kea in Hawaii, and he had just installed the first instrument on the brand-new 10-meter telescope at W. M. Keck Observatory. Matthews, who built the instrument—a near-infrared camera, abbreviated NIRC—was set to make the first scientific observations using the newly crowned Biggest Telescope in the World.

Bursts of Star Formation in the Early Universe

PASADENA, Calif.—Galaxies have been experiencing vigorous bursts of star formation from much earlier in cosmic history than previously thought, according to new observations by a Caltech-led team.

These so-called starburst galaxies produce stars at a prodigious rate—creating the equivalent of a thousand new suns per year. Now the astronomers have found starbursts that were churning out stars when the universe was just a billion years old. Previously, astronomers didn't know whether galaxies could form stars at such high rates so early in time.

Astronomers Observe Planets Around Another Star Like Never Before

PASADENA, Calif.—Thanks to a new high-tech gadget, astronomers have observed four planets orbiting a star relatively close to the sun in unprecedented detail, revealing the roughly ten-Jupiter-mass planets to be among the most exotic ones known.

The team, which includes several researchers from the California Institute of Technology (Caltech), describes its findings in a paper accepted for publication by the Astrophysical Journal.

Creating Indestructible Self-Healing Circuits

Imagine that the chips in your smart phone or computer could repair and defend themselves on the fly, recovering in microseconds from problems ranging from less-than-ideal battery power to total transistor failure. It might sound like the stuff of science fiction, but a team of Caltech engineers, for the first time ever, has developed just such self-healing integrated chips.

A Window Into Europa's Ocean Lies Right at the Surface

If you could lick the surface of Jupiter's icy moon Europa, you would actually be sampling a bit of the ocean beneath. So says Mike Brown, an astronomer at Caltech. Brown and Kevin Hand from the Jet Propulsion Laboratory (JPL) have found the strongest evidence yet that water from the vast liquid ocean beneath Europa's frozen exterior actually makes its way to the surface.

Visualizing Biological Networks in 4D

Every great structure, from the Empire State Building to the Golden Gate Bridge, depends on specific mechanical properties to remain strong and reliable. Rigidity—a material's stiffness—is of particular importance for maintaining the robust functionality of everything from colossal edifices to the tiniest of nanoscale structures. In biological nanostructures, like DNA networks, it has been difficult to measure this stiffness, which is essential to their properties and functions. But scientists at the California Institute of Technology (Caltech) have recently developed techniques for visualizing the behavior of biological nanostructures in both space and time, allowing them to directly measure stiffness and map its variation throughout the network.

Creating New Quantum Building Blocks

Laying the groundwork for an on-chip optical quantum network, a team of researchers, including Andrei Faraon from the California Institute of Technology (Caltech), has shown that defects in diamond can be used as quantum building blocks that interact with one another via photons, the basic units of light.

Caltech Senior Wins Churchill Scholarship

Caltech senior Andrew Meng has been selected to receive a Churchill Scholarship, which will fund his graduate studies at the University of Cambridge for the next academic year. Meng, a chemistry and physics major, was one of only 14 students nationwide who were chosen to receive the fellowship this year.

Sorting Out Stroking Sensations

The skin is a human being's largest sensory organ, helping to distinguish between a pleasant contact, like a caress, and a negative sensation, like a pinch or a burn. Previous studies have shown that these sensations are carried to the brain by different types of sensory neurons that have nerve endings in the skin. Only a few of those neuron types have been identified, however, and most of those detect painful stimuli. Now biologists at the California Institute of Technology (Caltech) have identified in mice a specific class of skin sensory neurons that reacts to an apparently pleasurable stimulus.


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