Caltech-led WormBase Project Awarded $14.8 Million by NIH

As many as 1 million nematode species are thought to live on Earth, and many are pests or parasites that ravage crops and spread diseases. They also happen to share many genes that are found in humans, and are intensively researched by labs around the world.

Team Led by Caltech Wins Second $10 Million Award for Research in Molecular Programming

During the past century, programmable technologies evolved from spinning gears and vacuum tubes to transistors and microchips. Now, a group of Caltech researchers and their colleagues at the University of Washington, Harvard University, and UC San Francisco are exploring how biologically important molecules—like DNA, RNA, and proteins—could be the next generation of programmable devices.

Caltech Researchers Synthesize Catalyst Important In Nitrogen Fixation

The industrial technique used to make nitrogen fertilizers mirrors the natural process of nitrogen fixation but requires high heat and pressure. Researchers at Caltech have synthesized a catalyst that allows for nitrogen fixation under much milder conditions.

Made-to-Order Materials

Caltech engineers have mimicked lightweight yet strong biological materials by creating nanostructured, hollow ceramic scaffolds, and have found that their small building blocks, or unit cells, display remarkable strength and resistance to failure despite being more than 85 percent air.

A Home for the Microbiome

The human body is full of tiny microorganisms—hundreds to thousands of species of bacteria collectively called the microbiome, which are believed to contribute to a healthy existence. The gastrointestinal (GI) tract—and the colon in particular—is home to the largest concentration and highest diversity of bacterial species. But how do these organisms persist and thrive in a system that is constantly in flux due to foods and fluids moving through it? A team led by California Institute of Technology (Caltech) biologist Sarkis Mazmanian believes it has found the answer, at least in one common group of bacteria: a set of genes that promotes stable microbial colonization of the gut.

Caltech Team Produces Squeezed Light Using a Silicon Micromechanical System

One of the many counterintuitive and bizarre insights of quantum mechanics is that even in a vacuum—what many of us think of as an empty void—all is not completely still. Low levels of noise, known as quantum fluctuations, are always present. Always, that is, unless you can pull off a quantum trick. And that's just what a team led by researchers at the California Institute of Technology (Caltech) has done.

Figuring Out Flow Dynamics

Since 2006, Beverley McKeon, professor of aeronautics and associate director of the Graduate Aerospace Laboratories at the California Institute of Technology (Caltech) and collaborator Ati Sharma, a senior lecturer in aerodynamics and flight mechanics at the University of Southampton in the U.K., have been working together to build models of turbulent flow. Recently, they developed a new and improved way of looking at the composition of turbulence near walls, the type of flow that dominates our everyday life. Their research could lead to significant fuel savings, as a large amount of energy is consumed by ships and planes, for example, to counteract turbulence-induced drag.

Pushing Microscopy Beyond Standard Limits

Engineers at the California Institute of Technology (Caltech) have devised a method to convert a relatively inexpensive conventional microscope into a billion-pixel imaging system that significantly outperforms the best available standard microscope. Such a system could greatly improve the efficiency of digital pathology.

Seeing Snow in Space

An international team of researchers, including Caltech's Geoffrey Blake, has used the Atacama Large Millimeter/submillimeter Array (ALMA) to capture the first image of a snow line around a Sun-like star. The findings appear in the current issue of Science Express.

Evidence for a Martian Ocean

Researchers at the California Institute of Technology (Caltech) have discovered evidence for an ancient delta on Mars where a river might once have emptied into a vast ocean. This ocean, if it existed, could have covered much of Mars's northern hemisphere—stretching over as much as a third of the planet.


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