Top 12 in 2012

Credit: Benjamin Deverman/Caltech

Gene therapy for boosting nerve-cell repair

Caltech scientists have developed a gene therapy that helps the brain replace its nerve-cell-protecting myelin sheaths—and the cells that produce those sheaths—when they are destroyed by diseases like multiple sclerosis and by spinal-cord injuries. Myelin ensures that nerve cells can send signals quickly and efficiently.

Credit: L. Moser and P. M. Bellan, Caltech

Understanding solar flares

By studying jets of plasma in the lab, Caltech researchers discovered a surprising phenomenon that may be important for understanding how solar flares occur and for developing nuclear fusion as an energy source. Solar flares are bursts of energy from the sun that launch chunks of plasma that can damage orbiting satellites and cause the northern and southern lights on Earth.

Coincidence—or physics?

Caltech planetary scientists provided a new explanation for why the "man in the moon" faces Earth. Their research indicates that the "man"—an illusion caused by dark-colored volcanic plains—faces us because of the rate at which the moon's spin rate slowed before becoming locked in its current orientation, even though the odds favored the moon's other, more mountainous side.

Choking when the stakes are high

In studying brain activity and behavior, Caltech biologists and social scientists learned that the more someone is afraid of loss, the worse they will perform on a given task—and that, the more loss-averse they are, the more likely it is that their performance will peak at a level far below their actual capacity.

Credit: NASA/JPL-Caltech

Eyeing the X-ray universe

NASA's NuSTAR telescope, a Caltech-led and -designed mission to explore the high-energy X-ray universe and to uncover the secrets of black holes, of remnants of dead stars, of energetic cosmic explosions, and even of the sun, was launched on June 13. The instrument is the most powerful high-energy X-ray telescope ever developed and will produce images that are 10 times sharper than any that have been taken before at these energies.

Credit: CERN

Uncovering the Higgs Boson

This summer's likely discovery of the long-sought and highly elusive Higgs boson, the fundamental particle that is thought to endow elementary particles with mass, was made possible in part by contributions from a large contingent of Caltech researchers. They have worked on this problem with colleagues around the globe for decades, building experiments, designing detectors to measure particles ever more precisely, and inventing communication systems and data storage and transfer networks to share information among thousands of physicists worldwide.

Credit: Peter Day

Amplifying research

Researchers at Caltech and NASA's Jet Propulsion Laboratory developed a new kind of amplifier that can be used for everything from exploring the cosmos to examining the quantum world. This new device operates at a frequency range more than 10 times wider than that of other similar kinds of devices, can amplify strong signals without distortion, and introduces the lowest amount of unavoidable noise.

Swims like a jellyfish

Caltech bioengineers partnered with researchers at Harvard University to build a freely moving artificial jellyfish from scratch. The researchers fashioned the jellyfish from silicon and muscle cells into what they've dubbed Medusoid; in the lab, the scientists were able to replicate some of the jellyfish's key mechanical functions, such as swimming and creating feeding currents. The work will help improve researchers' understanding of tissues and how they work, and may inform future efforts in tissue engineering and the design of pumps for the human heart.

Credit: NASA/JPL-Caltech

Touchdown confirmed

After more than eight years of planning, about 354 million miles of space travel, and seven minutes of terror, NASA's Mars Science Laboratory successfully landed on the Red Planet on August 5. The roving analytical laboratory, named Curiosity, is now using its 10 scientific instruments and 17 cameras to search Mars for environments that either were once—or are now—habitable.

Credit: Caltech/Michael Hoffmann

Powering toilets for the developing world

Caltech engineers built a solar-powered toilet that can safely dispose of human waste for just five cents per use per day. The toilet design, which won the Bill and Melinda Gates Foundation's Reinventing the Toilet Challenge, uses the sun to power a reactor that breaks down water and human waste into fertilizer and hydrogen. The hydrogen can be stored as energy in hydrogen fuel cells.

Credit: Caltech / Scott Kelberg and Michael Roukes

Weighing molecules

A Caltech-led team of physicists created the first-ever mechanical device that can measure the mass of an individual molecule. The tool could eventually help doctors to diagnose diseases, and will enable scientists to study viruses, examine the molecular machinery of cells, and better measure nanoparticles and air pollution.

Splitting water

This year, two separate Caltech research groups made key advances in the quest to extract hydrogen from water for energy use. In June, a team of chemical engineers devised a nontoxic, noncorrosive way to split water molecules at relatively low temperatures; this method may prove useful in the application of waste heat to hydrogen production. Then, in September, a group of Caltech chemists identified the mechanism by which some water-splitting catalysts work; their findings should light the way toward the development of cheaper and better catalysts.


In 2012, Caltech faculty and students pursued research into just about every aspect of our world and beyond—from understanding human behavior, to exploring other planets, to developing sustainable waste solutions for the developing world.

In other words, 2012 was another year of discovery at Caltech. Here are a dozen research stories, which were among the most widely read and shared articles from

Did we skip your favorite? Connect with Caltech on Facebook to share your pick.

H. Jeff Kimble to Receive Quantum Physics Award

The German Physical Society (Deutsche Physikalische Gesellschaft, or DPG) and the Optical Society of America (OSA) have selected Caltech physics professor H. Jeff Kimble to receive the Herbert Walther Award for his "pioneering experimental contributions to quantum optics, cavity quantum electrodynamics, and quantum information science."

The Miracle and Beauty of Physics: An Interview with Cliff Cheung

When you lift a paper clip off a table with a small magnet, you're accomplishing a remarkable feat: the tiny magnet is overcoming the gravitational pull from the entire Earth. Why does gravity seem so weak compared to electromagnetism and the other fundamental forces of nature? This vast discrepancy in scale—how a small magnet can beat out a whole planet—is related to what physicists call the hierarchy problem. Cliff Cheung—who joined Caltech this fall as an assistant professor of theoretical physics—is fascinated by this "very deep puzzle" (which may be solved through supersymmetry, a class of theories in which every fundamental particle has a partner particle, as well as by dark matter, the mysterious stuff that accounts for nearly a quarter of the universe). Recently, Cheung—who also plays guitar and piano, sings, and writes music—answered a few questions about coming to Caltech and his passion for physics.

A Sky Full of Planets

The confirmed count of planets in other solar systems has skyrocketed to more than 850, plus thousands of identified candidates. The opportunity to characterize so many solar systems has brought together Caltech planetary scientists and astronomers, who are forming a Center for Planetary Astronomy.

High-Energy Physicists Smash Records for Network Data Transfer

Physicists led by the California Institute of Technology (Caltech) have smashed yet another series of records for data-transfer speed. The international team of high-energy physicists, computer scientists, and network engineers reached a transfer rate of 339 gigabits per second (Gbps)—equivalent to moving four billion gigabytes per day, nearly doubling last year's record. The team also reached a new record for a two-way transfer on a single link by sending data at 187 Gbps between Victoria, Canada, and Salt Lake City.
Tuesday, April 9, 2013
Avery Library

Spring Teaching Assistant Orientation

Caltech Faculty Named AMS Fellows

Nine members of Caltech's faculty have been named to the inaugural class of Fellows of the American Mathematical Society (AMS).

Caltech Mourns the Passing of Wallace L. W. Sargent

Wallace L. W. Sargent, Ira S. Bowen Professor of Astronomy, Emeritus, at Caltech, passed away on October 29.

Two Faculty Members Named Packard Fellows

Two Caltech faculty members have been awarded Packard Fellowships for Science and Engineering. Biologist Alexei Aravin and astronomer John Johnson each were awarded $875,000, to be distributed over five years.

"I'm very excited about this fellowship," says Aravin, an assistant professor of biology. "It will allow my lab to pursue new, ambitious goals that are difficult to fund using traditional sources."

Noted Physicist Robert F. Christy Dies

Robert F. Christy, one of the last people alive to have worked on the Manhattan Project and whose later research in astrophysics contributed to our understanding of the size of the universe, passed away on October 3 at his home in Pasadena. The former provost and acting president of the California Institute of Technology (Caltech), where he was a longtime professor, was 96 years old.


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