Caltech Receives $12.3 Million to Train Scientific Leaders in Business and Industry

The California Institute of Technology (Caltech) has announced the creation of the Ronald and Maxine Linde Institute of Economic and Management Sciences. The initiative will bring together the best scientific minds and the best quantitative business practices, permitting a distinctive and targeted educational opportunity for Caltech's students and providing cutting-edge research opportunities for Caltech's faculty.

The new institute will be funded with an $8.2 million endowment established by Ronald and Maxine Linde and a $4.1 million addition to the endowment from the Gordon and Betty Moore matching program.

"Caltech students benefit greatly from exposure to the intellectual tools to become responsible, capable entrepreneurs and business managers," says Caltech's president, Jean-Lou Chameau. "By establishing the Linde Institute of Economic and Management Sciences, Ronald and Maxine Linde will foster the future growth of education and research activities that will prepare our students to assume leadership roles in industry and academia."

The new institute will be multidisciplinary, building on the success of Caltech's current Business, Economics, and Management (BEM) program by organizing its education and research activities into a single entity. BEM is an undergraduate option launched in 2002 and administered by the Division of the Humanities and Social Sciences (HSS).

The Linde Institute will be led by Peter Bossaerts, the William D. Hacker Professor of Economics and Management and professor of finance at Caltech, and will bring together current faculty while enhancing the Institute's ability to recruit additional scholars working in these areas.

"The new institute will enable Caltech to build on the excellence of its current research in the interdisciplinary areas that impact economics and management," says Ronald Linde, vice chair of Caltech's Board of Trustees. "It also will allow Caltech to equip its students with the proper background and tools to excel should they choose to become entrepreneurs or should they become involved in technology management."

Caltech is one of the few institutions at which such a program could be attempted, Linde adds, "because it combines an exceptional student population with a faculty that has chosen to pursue only the most analytically rigorous approach to business, economics, and management education."

"Caltech has taken a unique approach to the study of business," says HSS division chair Jonathan N. Katz. "Differing from a traditional business school model that is based primarily on inductively studying cases, Caltech's BEM program is rigorous, quantitative, and highly interdisciplinary. It provides students with analytical and conceptual tools to succeed in a modern, volatile business environment. To our knowledge, Caltech is the only institution to apply this social-scientific approach to undergraduate business education."

However, he adds, the BEM program—which is currently one of the most popular majors for students at Caltech—has "reached a threshold," requiring additional support to create a stronger infrastructure and unite the faculty working both within BEM and across Caltech's scientific disciplines.

"The Linde Institute will create a forum for sharing resources and making connections across campus," says Katz. "And it will foster the future growth and development of education and research activities."

The Lindes have sponsored numerous other scientific and research-intensive activities at Caltech, as well as a research facilities challenge grant. In 2008, the Lindes established an $18 million endowment at Caltech to create the Ronald and Maxine Linde Center for Global Environmental Science, which will be housed in a renovated 1930s laboratory. The Linde + Robinson Laboratory is scheduled to open in early 2012.

Lori Oliwenstein
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Caltech Neuroscientists Study "Fearless" Woman

Armed with tarantulas, snakes, and horror-movie clips, Caltech neuroscientists, together with collaborators at the University of Iowa and the University of Southern California (USC), have studied a woman who is unable to experience the emotion of fear.

The work, described in the December 16 online issue of the journal Current Biology, provides the first in-depth investigation of how the experience of fear depends on a specific brain region called the amygdala and offers new insight into our conscious experience of emotions. The amygdalae, which register rapid emotional reactions, are implicated in depression, anxiety, and autism.

The individual, a woman known as SM who has extensive damage to the amygdala on both sides of her brain—rendering the brain regions essentially non-functional—showed no fear when subjected to numerous situations that normally induce the emotion.

The research team measured fear behavior by videotaping the subject as she walked through a haunted house at Halloween, handled large tarantulas and snakes in an exotic pet store, and viewed frightening film clips from horror movies. Detailed questionnaires and interviews were used to explore her experience of fear in response to all these situations, and during the day-to-day events in her real life.

"The complete absence of any fear behavior, or any report of subjective fear experience, was truly remarkable," says Justin Feinstein, a graduate student in clinical psychology at the University of Iowa and first author on the study. "This was especially striking because SM can feel emotions other than fear normally. This was not a subtle impairment, but something that just hit you in the face."

The other members of the research team were Ralph Adolphs, the Bren Professor of Psychology and Neuroscience at Caltech; Antonio Damasio, Dornsife Professor of Neuroscience and Director of the Brain and Creativity Institute at USC; and Daniel Tranel, Professor of Psychology and Neurology at the University of Iowa. The investigators have a long history of collaboration using an expansive registry of brain lesion patients at the University of Iowa.

According to Adolphs, the findings are especially valuable in light of the large amount of research on the amygdala in animals showing that the brain region is important for fear behaviors and fear learning. "One thing you simply cannot measure definitively in animals is their conscious experience of fear," Adolphs argues. "This study really fills an important open question; we had all assumed that the amygdala would be important for many aspects of fear processing, but demonstrating it also plays a role in feeling fear was not trivial to do."

In addition, Tranel says, "these findings will be of special importance to understanding psychiatric illnesses in which the amygdala is thought to be dysfunctional, such as depression, PTSD, and phobias."

Kathy Svitil

Alvarez on Alaska

Alaska's controversial and still-undecided Senate race between Republican Joe Miller and current Republican Senator Lisa Murkowski—who Miller beat in the primary and who then mounted a write-in campaign—may come down to a court challenge over the 92,500 write-in ballots cast. In his latest election-blog entry, Michael Alvarez—co-director of the Caltech/MIT Voter Technology Project—notes that, despite the brouhaha, 89 percent of the write-in voters somehow "managed to get Murkowski's name spelled correctly." Alvarez says that no matter which way this particular contest eventually goes, the real lesson may be in the success of the Murkowski campaign's efforts "to inform Alaskan voters how to cast a correct write-in ballot," and how that information might be used in the future by other campaigns in other states.


Lori Oliwenstein

The Polls Are Closed . . .

Calling last Tuesday's elections "historic" and "one of the most important midterm elections in recent memory," Caltech political scientist R. Michael Alvarez weighed in on the contrasts between the national and local results in an op-ed entitled, "GOP Tidal Wave Stopped at State Line," published in Sunday's Pasadena Star-News.

What made the difference? A number of factors, says Alvarez. "[I]t is likely that California's electorate on Tuesday was distinct from the rest of the nation," he writes. "As I visited polling places on Tuesday, in many parts of Los Angeles County there were energized voters, and visible voter-mobilization efforts. Early analysis of exit poll data indicates that those efforts might have led to a significant increase in Latino participation, another possible reason Republicans failed throughout the state."

To read more of Alvarez's analysis of the election results, go to the Pasadena Star-News. Or, for more research, analysis, and commentary on the election, visit the Caltech/MIT Voting Technology Project blog.

Lori Oliwenstein
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What You See Affects What You Want

Visual attention guides the choices we make.

When it comes to making choices, say Caltech's Antonio Rangel and his colleagues, much depends on which items catch—and keep—your eye.

"We're interested in how the brain makes simple choices, like which item to pick from a buffet table," says Rangel, professor of neuroscience and economics. "Why is it that when we look at the buffet table, our gaze shifts back and forth between the items in order to make a choice? What is the role of visual attention in all this?"

To find out, Rangel—along with Caltech postdoctoral scholar Ian Krajbich and Stanford University's Carrie Armel—designed a mathematical model to describe the impact of what they call "visual fixation" on the making of these sorts of choices. (Simply put, visual fixation is the amount of time you spend gazing in one direction or at one item versus another.) They recently published their research online in the journal Nature Neuroscience.

"The model makes very specific predictions about how the pattern of fixation is related to our choices," Rangel explains. "For example, after controlling for other variables, items that are looked at more should be chosen more often."

But are they? To make sure, the team carried out an eye-tracking experiment in which subjects were shown pairs of food items on a computer screen, allowed to look at the items for as long as they wanted, and then were asked to choose one or the other. While the subjects gazed, the researchers tracked the movements of their eyes.

Just as predicted, the item a subject looked at longest was the one he or she most often picked—nearly three-quarters of the time, in fact.

Interesting stuff on its own merit, right? It also has implications for the business world—putting increased emphasis on things like packaging and in-store displays. "[T]he model explains how cultural norms (for example, reading left to right) can interact with comparator processes to produce cultural choice biases," the scientists write. "These biases help to explain, for example, why shelf and computer screen space on the top-left is more valuable than other positions."

Lori Oliwenstein

Consumers Will Pay More for Goods They Can Touch, Caltech Researchers Say

PASADENA, Calif.—We've all heard the predictions: e-commerce is going to be the death of traditional commerce; online shopping spells the end of the neighborhood brick-and-mortar store.

While it's true that online commerce has had an impact on all types of retail stores, it's not time to bring out the wrecking ball quite yet, says a team of researchers from the California Institute of Technology (Caltech).

Their investigations into how subjects assign value to consumer goods—and how those values depend on the way in which those goods are presented—are being published in the September issue of the American Economic Review.

The question they address is at the heart of economics and marketing: Does the form in which an item is presented to consumers affect their willingness to pay for it?

Put more simply, says Antonio Rangel, professor of neuroscience and economics at Caltech, "At a restaurant, does it matter whether they simply list the name of the dessert, show a picture of the dessert, or bring the dessert cart around?"

Most behavioral theories assume that the form of the presentation should not matter, notes Caltech graduate student Benjamin Bushong. "Some models suggest that choices amongst objects shouldn't vary with their descriptions or by the procedure by which the choice is made," he says. "However, our experiments show that the form in which the items are presented matters a lot. In fact, our research measures in monetary terms just how much those different displays matter."

Initially, the Caltech team made these measurements by presenting foods to hungry subjects in three different forms: in a text-only format; in a high-resolution photograph; and in a tray placed in front of the subjects. "Then we measured their willingness to pay for the food," explains Rangel.

As it turned out, there was no difference between the values subjects put on the food depicted in the text and in the picture. But the bids on the food on the tray right in front of the subjects were an average of 50 percent higher than the bids on either of the other two presentations.

"We were quite surprised to find that the text display and the image display led to similar bids," admits Bushong. "Initially, we thought people would bid more in the face of more information or seemingly emotional content. This finding could explain why we don't see more pictorial menus in restaurants—they simply aren't worth the cost!"

While the food experiments' results were intriguing, says Rangel, "We couldn't stop there." After all, the smell of the food might have made it more appealing to the experiment's subjects. And so, to take that variable out of play, the team chose different "goods" to present—a variety of trinkets from the Caltech bookstore—and again measured the effect of display on willingness to pay.

The results were the same as during the food experiments. The subjects were willing to pay, on average, 50 percent more for items they could reach out and touch than for those presented in text or picture form. "We knew then that whatever is driving this effect is a more general response," says Rangel.

But what was driving the effect? The team's initial hypothesis was that the behavior is driven by a classic Pavlovian response. "Behavioral neuroscience suggests that when I put something appetizing in front of you, your brain activates motor programs that lead to your making contact with that item and consuming it," Rangel explains. "We hypothesized that if there's no way for you to touch the item, then the Pavlovian motor response would be absent, and your drive to consume the item thus significantly lessened."

To test this hypothesis, the team put up a plexiglass barrier between the subject and the items up for bid. And, as predicted, once the possibility of physical contact with the item had been extinguished, the value the subjects gave to that item dropped to the same level as the text- and picture-based items.

"Even if you don't touch the item," says Rangel, "the fact that it is physically present seems to be enough. This Pavlovian response is more likely to be deployed when making contact with the stimulus is a possibility."

What does all this mean in the real world? At the very least, it suggests that your local bookstore—where you can reach out and ruffle a paperback's pages—may have more staying power than e-commerce experts might think.

In addition to Rangel and Bushong, the coauthors on American Economic Review paper, "Pavlovian Processes in Consumer Choice: The Physical Presence of a Good Increases Willingness-to-pay," are former Caltech undergraduate student Lindsay King and Colin Camerer, the Robert Kirby Professor of Behavioral Economics. Their work was supported by the Gordon and Betty Moore Foundation.

Lori Oliwenstein

Learning Strategies are Associated with Distinct Neural Signatures

PASADENA, Calif.—The process of learning requires the sophisticated ability to constantly update our expectations of future rewards so we may make accurate predictions about those rewards in the face of a changing environment. Although exactly how the brain orchestrates this process remains unclear, a new study by researchers at the California Institute of Technology (Caltech) suggests that a combination of two distinct learning strategies guides our behavior. 

A paper about the work will appear in the May 27 issue of the journal Neuron.

One accepted learning strategy, called model-free learning, relies on trial-and-error comparisons between the reward we expect in a given situation and the reward we actually get. The result of this comparison is the generation of a "reward prediction error," which corresponds to that difference. For example, a reward prediction error might correspond to the difference between the projected monetary return on a financial investment and our real earnings.

In the second mechanism, called model-based learning, the brain generates a cognitive map of the environment that describes the relationship between different situations. "Model-based learning is associated with the generation of a 'state prediction error,' which represents the brain's level of surprise in a new situation given its current estimate of the environment," says Jan Gläscher, a postdoctoral scholar at Caltech and the lead author of the study.

"Think about a situation in which you always take the same route when driving home after work, but on a particular day the usual way is blocked due to construction work," Gläscher says. "A model-free learning system would be helplessly lost; it is only concerned with taking actions that in the past were rewarding, so if those actions are no longer available it wouldn't be able to decide where to go next. But a model-based system would be able to query its cognitive map and figure out an efficient detour using an alternative route."

"Although the simpler model-free learning mechanism has been well studied and its basic learning mechanism—which is driven by reward prediction errors—is relatively well understood, the mechanisms underlying the more sophisticated model-based learning system, with its rich adaptability and flexibility, are less well understood" says John P. O'Doherty, professor of psychology at Caltech and the Thomas N. Mitchell Professor of Cognitive Neuroscience at Trinity College in Dublin, Ireland.

To further characterize the neurological underpinnings of these two learning systems, Gläscher, O'Doherty, and their colleagues designed a computer-based decision-making task that allowed them to measure when and where the brain computes both reward and state prediction error signals, and to determine if the two types of errors actually produce different neural signatures. 

In the task, subjects had to make choices between a left and right movement that allowed them to shift between different "states"—denoted by graphical icons—in a virtual environment; the process is similar to that of navigating around in a simple video game. Each left-or-right choice made in this virtual environment led the subject to a new state. Their objective was to reach a particular goal state to obtain a monetary reward, "and their chances of ending up in that goal state strongly depended on the particular pattern of sequential choices they made," O'Doherty explains.

A model-based system can learn about the structure of the virtual environment and then use this information to compute the actions needed to get to the reward state, in a manner analogous to how a chess player might try to think through the sequential chess moves needed to win a match. A model-free system, on the other hand, would only learn to blindly choose those actions that gave reward in the past, without evaluating the consequences in the current situation.

Eighteen participants were scanned using functional magnetic resonance imaging as they learned the task. The brain scans showed the distinctive, previously characterized neural signature of reward prediction error—generated during model-free learning—in an area in the middle of the brain called the ventral striatum. During model-based learning, however, the neural signature of a state prediction error appeared in two different areas on the surface of the brain in the cerebral cortex: the intraparietal sulcus and the lateral prefrontal cortex. 

These observations suggest that two unique types of error signals are computed in the human brain, occur in different brain regions, and may represent separate computational strategies for guiding behavior. "A model-free system operates very effectively in situations that are highly automated and repetitive—for example, if I regularly take the same route home from work," Gläscher says, "whereas a model-based system, although requiring much greater brain-processing power, is able to adapt flexibly to novel situations, such as needing to find a new route following a roadblock." 

These two distinct learning mechanisms serve complementary roles in controlling human behavior, Gläscher says. "Because the processing power of our brains is limited, it doesn't make sense to deploy the more computationally intensive model-based system for controlling everything we do. Instead, it is better to rely on the model-free system for a lot of our everyday behavior and use the model-based system only for new or complex situations. An important area for further research will be to try to understand the factors governing how these systems interact together in order to control behavior, and to determine how this is implemented in the brain."

The other coauthors on the paper, "States versus rewards: Dissociable neural prediction error signals underlying model-based and model-free reinforcement learning," are Nathaniel Daw of New York University and Peter Dayan of University College London. The work was supported by the Gordon and Betty Moore Foundation, the National Institute of Mental Health, the German Academy of Natural Sciences Leopoldina, and the Gatsby Charitable Foundation.

Kathy Svitil

Burton H. Klein, 92

Burton H. Klein, professor of economics, emeritus, at the California Institute of Technology (Caltech) passed away on February 12 at a retirement home in Santa Barbara, California. He was 92.

An expert in dynamic economics, Klein was particularly interested in the economics of innovation and how it related to organizational structure.

Born October 16, 1917, in Minneapolis, Minnesota, Klein received both his AB (1940) and his PhD (1948) from Harvard. After stints with the U.S. Strategic Bombing Survey-where he worked with noted economist John Kenneth Galbraith on an overall economic assessment of the German mobilization prior to World War II-he became a staff member of the President's Council for Economic Advisors serving from 1948 to 1952.  Klein's work in Germany led to his 1959 book, Germany's Economic Preparations for War, a widely cited publication detailing that country's economic policies leading into the war.  

Klein joined the RAND Corporation in 1952 and, in 1961, became head of RAND's economics department. He served as special assistant to the U.S. Secretary of Defense from 1963 to 1965, and in 1967 he joined Caltech as professor of economics. He became emeritus in 1983.

Klein also served as a consultant to the Bureau of Budget, the Arms Control and Disarmament Agency, the Brookings Institution, and the Swedish and Israeli governments.

At Caltech, Klein took lessons learned from other disciplines when looking at economic considerations. In his 1977 book, Dynamic Economics, he contrasted a static concept of stability with a dynamic concept. He argued that unpredictable behavior at the micro level leads to smooth progress at the macro level. And in his 1984 book, Prices, Wages, and Business Cycles: A Dynamic Theory, he provided a statistical demonstration of how the quest for micro stability, especially if aided by government, can lead to increasingly larger economic downturns.

"My basic thesis is that firms in industries that lack significant challenges become overcentralized, inflexible, and highly incapable of dealing with all kinds of negative feedback," said Klein when he spoke of his 1984 book. "This means that, instead of dealing with risks, they can transmit these risks to the public at large, especially if they are aided by the federal government."

His later interests were in explaining the particular behaviors necessary to assure the long-run survival of firms.

Klein continued his passion for writing long after his retirement. He was working on a new book at the time of his passing.

His family noted he also maintained his interest in current affairs and politics, even campaigning for Barack Obama at his retirement home.

An avid woodworker, Klein kept up his interest by crafting furniture and clocks. 

Jon Weiner
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African-American Babies and Boys Least Likely to Be Adopted, Study Shows

Chance of adoption also drops after baby's birth, say economists from Caltech, NYU, and the London School of Economics

PASADENA, Calif.— Parents pursuing adoption within the United States have strong preferences regarding the types of babies they will apply for, tending to choose non-African-American girls, and favoring babies who are close to being born as opposed to those who have already been born or who are early in gestation. These preferences are significant, according to the findings of a team of economists from the California Institute of Technology (Caltech), the London School of Economics, and New York University (NYU), and can be quantified in terms of the amount of money the potential adoptive parents are willing to pay in finalizing their adoption.

While the data are intriguing, the real value of the study, the researchers say, is that it can give policymakers a more rational, evidence-driven base from which to consider the implications of policies and laws, such as those that restrict adoption by single-sex and foreign couples.

The key to these findings, the research team says, was the data set they were able to put together. "These data are unique," says Leeat Yariv, associate professor of economics at Caltech.

What makes them so unusual? Detailed data on adoption generally are difficult to come by. The researchers, however, were able to gather information—from a website run by an adoption intermediary—over a five-year period (between 2004 and 2009). The intermediary works to bring together—to match—potential adoptive parents with birth mothers seeking to relinquish their children for adoption.

Achieving such a match is not an easy task, says Leonardo Felli, professor of economics at the London School of Economics. He notes that adoption in the United States has "been characterized, for years, by two conflicting imbalances: On the one hand, a considerable number of potential adoptive parents are left unmatched. On the other hand, the number of children who are not adopted and end up in the foster-care system is disproportionately high."

Hence the need for adoption facilitators, says Yariv. "The website operates somewhat like an online real estate site," she explains. "We could see the attributes of the children—race, gender, age—and even the finalization costs, or the amount of money the adoptive parent would need to pay to finalize the adoption. In addition, we could see which children the potential adoptive parents applied for."

In other words, the team could see which babies attracted interest from potential adoptive parents, and determine which traits were most likely to lead to a successful adoption. This revealed three main patterns.

First, the researchers found that a non-African-American baby is seven times more likely to "attract the interest and attention of potential adoptive parents than an African-American baby," says Felli. This difference, he adds, is not seen when comparing parents' preferences for Caucasian versus Hispanic babies—a finding that is somewhat surprising, given that the adoptive parents in the sample are all Caucasian.

The second pattern shown was the gender preference. "A girl has a higher—by slightly more than one-third—chance of attracting the attention of potential adoptive parents than a boy," says Felli.

The preference for girls is arguably unexpected. "With biological children, the literature shows that there's a slight but significant preference for boys over girls," says Yariv. "But, in adoption, there's a very strong preference for girls over boys."

These preferences come with what is essentially a price tag, the researchers note. The data showed that parents are willing to pay an average of $16,000 more in finalization costs for a girl as opposed to a boy, says Yariv—and $38,000 more for a non-African-American baby than for an African-American baby.

Mariagiovanna Baccara, assistant professor at NYU's Stern School of Business, says these results are especially interesting because "the same race and gender biases persist across all categories of adoptive parents that we identified." In fact, she says, "the gender bias in favor of girls is somewhat stronger for both gay men and lesbian couples."

The researchers also found that the interest of potential adoptive parents in a particular baby depends on the stage of gestation. "While unborn children become increasingly attractive over the birth mother's pregnancy, probably because the match involves less uncertainty from the adoptive parents' perspective," says Baccara, "we find that the desirability of a child decreases dramatically right after birth." This means, Baccara adds, that “bureaucratic obstacles disrupting an adoption plan at the time of birth are extremely detrimental to the future prospects of the child.”

The economists feel their data should be used to address some of the existing political debates concerning the U.S. domestic adoption process.

The first involves the restrictions some states impose on same-sex and single-parent adoptions; the second involves the 2008 Hague treaty, which placed significant roadblocks in the path of potential parents from other countries who want to adopt children from the United States.

To assess the impact these restrictions have on the successful placement of children for adoption, the researchers turned to the data they had collected.

In one analysis, the researchers dropped all same-sex parents from their data set. When they did this, the number of successful matches dropped too—by 6 percent. "This is a substantial amount," says Felli, "considering that only 18 percent of the birth mothers in our pool allow adoption by same-sex couples in the first place."

Excluding foreign parents from the pool had an even greater effect—producing a 33 percent decline in the number of babies successfully placed with an adoptive family.

Yariv thinks this remarkably steep decline may have to do with the fact that foreign parents have "more flexible" preferences.

"These data suggest that caution should be used in some of these political debates," says Felli. "When asking whether adopted children should find a home with a single-sex or foreign family as opposed to a U.S. heterosexual family, one should account for the considerable chance that the child in question may not be matched with a family at all and will end up in foster care instead."

"And statistically," Yariv adds, "long-term foster care leads to bad outcomes."

To see how such bad outcomes can be avoided the team will look at alternatives to the U.S. adoption system.

"In most European countries," Yariv explains, "there’s a more centralized system, where effectively a judge makes the matches. We'd like to see how much efficiency we'd gain or lose by looking at intermediate levels of this kind of centralization."

The paper, "Gender and Racial Biases: Evidence from Child Adoption," was also coauthored by Allan Collard-Wexler of NYU's Stern Business School.

An abstract of the paper, released by London's Centre for Economic Policy Research, can be found at The full, unpublished, text of the paper can be found at

Lori Oliwenstein

Caltech Receives More than $33 Million from American Recovery and Reinvestment Act

Neuroeconomics and the fundamentals of jet noise just some of the many projects supported

PASADENA, Calif.-Research in genomic sciences, astronomy, seismology, and neuroeconomics are some of the many projects being funded at the California Institute of Technology (Caltech) by the American Recovery and Reinvestment Act (ARRA).

As part of the federal government program of stimulating the economy, ARRA is providing approximately $21 billion for research and development. The goal is for the funding to lead to new scientific discoveries and to support jobs.

ARRA provides the funds to federal research agencies such as the National Institutes of Health, the National Science Foundation, and the Department of Energy, which then support proposals submitted by universities and other research institutions from across the country.

Caltech has received 82 awards to date, totaling more than $33 million. Spending from the grants began in the spring of 2009 and thus far has led to the support of 93 jobs at the Institute.

"This funding will help lead to substantive and important work here at Caltech," says Caltech president Jean-Lou Chameau. "We're grateful to have this opportunity to advance research designed to benefit the entire country."

For biologist Paul Sternberg, the Thomas Hunt Morgan Professor of Biology at Caltech and a Howard Hughes Medical Institute investigator, the ARRA funds mean an opportunity to improve upon WormBase, an ongoing multi-institutional effort to make genetic information on the experimental animal C. elegans freely available to the world.

"All biological and biomedical researchers rely on publicly available databases of genetic information," says Sternberg. "But it has been expensive and difficult to extract information from scientific research articles. We have developed some tools to make it less expensive and less tedious to get the job done, for WormBase and many other groups."

Sternberg's ARRA funds-$989,492-will go towards developing a more efficient approach to extracting key facts from published biological-science papers.

Among the other diverse Caltech projects receiving ARRA funds are:

  • a catalog of jellyfish DNA;
  • improving the speed of data collection at Caltech's Center of Excellence in Genomic Science;
  • studies into the fundamentals of particle physics;
  • the California High School Cosmic Ray Observatory (CHICOS) program, which provides high school students access to cosmic ray research;
  • the search for new astronomical objects such as flare stars and gamma-ray bursts, and the means to make those discoveries accessible to the public; and
  • a $1 million upgrade of the Southern California Seismic Network.

Caltech Professor of Mechanical Engineering Tim Colonius received ARRA funds for research into better understanding how noise is created by turbulence in the exhaust of turbofan aircraft engines and what might be done to mitigate it. Jet noise is an environmental problem subject to increasingly severe regulation throughout the world.

"To meet the ambitious noise-reduction goals under discussion, a greatly enhanced understanding of the basic physics is needed," says Colonius. "Very large-scale computer simulations and follow-up analyses will bring us much closer to the goal of discovering the subtle physical mechanisms responsible for the radiation of jet noise and allow us to develop methods for suppressing it."

Colonius received $987,032 in ARRA funds from the National Science Foundation.

Colin Camerer, the Robert Kirby Professor of Behavioral Economics, received his ARRA funds to explore the application of neurotechnologies to solving real-life economic problems.

"Our project, with my Caltech colleague Antonio Rangel, will explore the psychological and neural correlates of value and decision-making and their use in improving the efficiency of social allocations," says Camerer.

Camerer and his colleagues previously found that they could use information obtained through functional magnetic resonance imaging measurements to develop solutions to economic challenges.

Rangel, an associate professor of economics, has a second ARRA-funded project to analyze the neuroeconomics of self-control in dieting populations.

"Funding of this nature is critical to much of the work we do here at Caltech," adds Chameau. "And with ARRA support, dramatic discoveries may be just around the corner."

For a complete list of ARRA projects, visit:

# # #

About Caltech:

Caltech is recognized for its highly select student body of 900 undergraduates and 1,200 graduate students, and for its outstanding faculty. Since 1923, Caltech faculty and alumni have garnered 32 Nobel Prizes and five Crafoord Prizes.

In addition to its prestigious on-campus research programs, Caltech operates the Jet Propulsion Laboratory (JPL), the W. M. Keck Observatory in Mauna Kea, the Palomar Observatory, and the Laser Interferometer Gravitational-Wave Observatory (LIGO). Caltech is a private university in Pasadena, California. For more information, visit

Jon Weiner
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