New Radiation-free Targeted Therapy Detects and Eliminates Breast-Cancer Tumors in Mice

Combining a compound known as a gallium corrole with a protein carrier results in a targeted cancer therapy that is able to detect and eliminate tumors in mice with seemingly fewer side effects than other breast-cancer treatments, says a team of researchers from the California Institute of Technology (Caltech), the Israel Institute of Technology (Technion) and the Cedars-Sinai Medical Center.

Caltech Scientists Create New Enzymes for Biofuel Production

Researchers at Caltech and world-leading gene-synthesis company DNA2.0 have taken an important step toward the development of a cost-efficient process to extract sugars from cellulose--the world's most abundant organic material and cheapest form of solar-energy storage. Plant sugars are easily converted into a variety of renewable fuels such as ethanol or butanol.

Caltech and UCSD Researchers Shed Light on How Proteins Find Their Shapes

Researchers from the California Institute of Technology (Caltech) and the University of California at San Diego (UCSD) have brought together UCSD theoretical modeling and Caltech experimental data to show just how amino-acid chains might fold up into unique, three-dimensional functional proteins.  

Self-Regulating Molecular "Transformers" Control the Intracellular Delivery of Proteins

Scientists from the California Institute of Technology (Caltech) have uncovered the Transformer like properties of molecules responsible for carrying and depositing proteins to their correct locations within cells. The research could eventually lead to novel treatments for diseases that result from flaws in protein delivery as well as the development of new types of antibiotics.

Caltech 4D Microscope Revolutionizes the Way We Look at the Nano World

More than a century ago, the development of the earliest motion picture technology made what had been previously thought "magical" a reality: capturing and recreating the movement and dynamism of the world around us. A breakthrough technology has now accomplished a similar feat, but on an atomic scale--by allowing, for the first time, the real-time, real-space visualization of fleeting changes in the structure and shape of matter barely a billionth of a meter in size.

Four Caltech Faculty Members Named Among 100 Chemical Engineers of the Modern Era

Four members of the 11-member chemical engineering faculty at the California Institute of Technology (Caltech) were honored by the American Institute of Chemical Engineers (AIChE) in their list of 100 Chemical Engineers of the Modern Era, published in the October issue of their magazine, Chemical Engineering Progress.

Caltech Engineers Build First-Ever Multi-Input "Plug-and-Play" Synthetic RNA Device

Engineers from the California Institute of Technology (Caltech) have created a "plug-and-play" synthetic RNA device--a sort of eminently customizable biological computer--that is capable of taking in and responding to more than one biological or environmental signal at a time.

Caltech Researcher Awarded $10 Million Grant

Brian M. Stoltz, the Ethel Wilson Bowles and Robert Bowles Professor of Chemistry at the California Institute of Technology (Caltech), has been awarded a $10 million grant from the King Abdullah University of Science and Technology (KAUST).

Caltech Engineers Build Mini Drug-Producing Biofactories in Yeast

Researchers at the California Institute of Technology have developed a novel way to churn out large quantities of drugs, including antiplaque toothpaste additives, antibiotics, nicotine, and even morphine, using mini biofactories--in yeast.

Caltech Scientists Awarded $20 Million to "Power the Planet"

In the dreams of Harry Gray, Beckman Professor of Chemistry at the California Institute of Technology, the future energy needs of the world are met with solar-fuel power plants. Now, a $20 million award from the Chemical Bonding Center (CBC), a National Science Foundation (NSF) Division of Chemistry program, will help bring this dream one step closer to reality.

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