Caltech Researchers Create New Proteins by Recombining the Pieces of Existing Proteins

An ongoing challenge in biochemistry is getting a handle on protein folding-that is, the way that DNA sequences determine the unique structure and functions of proteins, which then act as "biology's workhorses." Gaining mastery over the construction of proteins will someday lead to breakthroughs in medicine and pharmaceuticals.

Watson Lecture: Revolutionary Medicine

Imagine taking a medicine that is not only ideally suited for treating your particular ailment but also perfectly designed for YOU and your own unique genetic makeup.

Caltech Researchers Achieve First Electrowetting of Carbon Nanotubes

If you can imagine the straw in your soda can being a million times smaller and made of carbon, you pretty much have a mental picture of a carbon nanotube. Scientists have been making them at will for years, but have never gotten the nanotubes to suck up liquid metal to form tiny wires. In fact, conventional wisdom and hundreds of refereed papers say that such is not even possible.

Researchers uncover new details about how signals are transmitted in the brain

An international team of scientists has announced a new breakthrough in understanding the molecular details of how signals move around in the human brain. The work is basic research, but could help pharmacologists design new drugs for treating a host of neurological disorders, as well as drugs for reducing alcohol and nicotine craving.

Caltech Chemist Robert Grubbs Wins Nobel Prize

Robert Grubbs, an organic chemist whose work on catalysis has led to a wide variety of applications in medicine and industry, has won the 2005 Nobel Prize in chemistry. The announcement was made this morning by the Royal Swedish Academy of Sciences in Stockholm.

Scientists Uncover Rules that Govern the Rate of Protein Evolution

Humans and insects and pond scum-and all other living things on Earth-are constantly evolving. The tiny proteins these living things are built from are also evolving, accumulating mutations mostly one at a time over billions of years. But for reasons that hitherto have been a mystery, some proteins evolve quickly, while others take their sweet time-even when they reside in the same organism.

Caltech, MIT Chemists Look for Better Waysto Use Chemical Bonds to Store Solar Energy

With gasoline prices hovering at $3 per gallon, probably few Americans need convincing that another energy crisis is imminent. But what precisely is to be done about our future energy needs is still a puzzle. There's talk about a "hydrogen economy," but hydrogen itself poses some formidable challenges.

All-Female Chemical Engineering Graduating Class at Caltech This Year

"I am not a novelty. . . It is not amazing that girls are engineers-it's normal," says Victoria Loewer, a member of the class of 2005 at the California Institute of Technology. Loewer is referring to the fact that she is a member of the first all-female chemical engineering graduating class at Caltech, a significant milestone in the history of the Institute.

Caltech Chemical Biologist SpecializingIn Brain Chemistry Named HHMI Investigator

California Institute of Technology chemical biologist Linda Hsieh-Wilson has been named one of this year's new Howard Hughes Medical Institute Investigators. Hsieh-Wilson's research integrates chemistry and neurobiology to understand how the cells of the brain communicate with one another.

Toward a Longer, Healthier Life

In two separate awards from the Ellison Medical Foundation, two scientists from the California Institute of Technology are taking a much more scholarly approach to the ravages of aging. Harry Gray, a chemist, has been awarded $970,000 to reveal the structure of a protein and a peptide that underlie two age-related diseases, Alzheimer's and Parkinson's, while biologist Alexander Varshavsky has been awarded $972,000 to conduct a systematic investigation of the genetics and biochemistry of aging.


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