Caltech Scientists Develop DNA Origami Nanoscale Breadboards for Carbon Nanotube Circuits

In work that someday may lead to the development of novel types of nanoscale electronic devices, an interdisciplinary team of researchers at the California Institute of Technology (Caltech) has combined DNA's talent for self-assembly with the remarkable electronic properties of carbon nanotubes, thereby suggesting a solution to the long-standing problem of organizing carbon nanotubes into nanoscale electronic circuits.

Caltech and IBM Scientists Use Self-Assembled DNA Scaffolding to Build Tiny Circuit Boards

Scientists at the Caltech and IBM's Almaden Research Center have developed a new technique to orient and position self-assembled DNA shapes and patterns--or "DNA origami"--on surfaces that are compatible with today's semiconductor manufacturing equipment. These precisely positioned DNA nanostructures, each no more than one one-thousandth the width of a human hair, can serve as scaffolds or miniature circuit boards for the precise assembly of computer-chip components.

Caltech Researchers Show How Organic Carbon Compounds Emitted by Trees Affect Air Quality

A previously unrecognized player in the process by which gases produced by trees and other plants become aerosols—microscopically small particles in the atmosphere—has been discovered by a research team led by scientists at the California Institute of Technology (Caltech). Their research on the creation and effects of these chemicals, called epoxides, is being featured in this week's issue of the journal Science.

 

Caltech Chemists Say Antibody Surrogates Are Just a "Click" Away

Chemists at the California Institute of Technology (Caltech) and the Scripps Research Institute have developed an innovative technique to create cheap but highly stable chemicals that have the potential to take the place of the antibodies used in many standard medical diagnostic tests.

Caltech Researchers Explore How Cells Reconcile Mixed Messages in Decisions About Growth

The cells in our body are constantly receiving mixed messages. An epithelial cell might be exposed to one signal telling it to divide and, simultaneously, another telling it to stop dividing. The tug-of-war between these two sets of influences, and the effects they have on tissue growth, are explained and explored in a paper authored by scientists from Caltech and published online in the Proceedings of the National Academy of Sciences.

Harry Gray Awarded for Lifetime of Basic Research in Chemistry and Advances in Solar Fuel

Harry Gray, the Beckman Professor of Chemistry and founding director of the Beckman Institute at Caltech, has been named the recipient of the 2009 Welch Award in Chemistry. The award is presented annually by the Houston-based Welch Foundation for lifetime achievement in basic research.

New Radiation-free Targeted Therapy Detects and Eliminates Breast-Cancer Tumors in Mice

Combining a compound known as a gallium corrole with a protein carrier results in a targeted cancer therapy that is able to detect and eliminate tumors in mice with seemingly fewer side effects than other breast-cancer treatments, says a team of researchers from the California Institute of Technology (Caltech), the Israel Institute of Technology (Technion) and the Cedars-Sinai Medical Center.

Caltech Scientists Create New Enzymes for Biofuel Production

Researchers at Caltech and world-leading gene-synthesis company DNA2.0 have taken an important step toward the development of a cost-efficient process to extract sugars from cellulose--the world's most abundant organic material and cheapest form of solar-energy storage. Plant sugars are easily converted into a variety of renewable fuels such as ethanol or butanol.

Caltech and UCSD Researchers Shed Light on How Proteins Find Their Shapes

Researchers from the California Institute of Technology (Caltech) and the University of California at San Diego (UCSD) have brought together UCSD theoretical modeling and Caltech experimental data to show just how amino-acid chains might fold up into unique, three-dimensional functional proteins.  

Self-Regulating Molecular "Transformers" Control the Intracellular Delivery of Proteins

Scientists from the California Institute of Technology (Caltech) have uncovered the Transformer like properties of molecules responsible for carrying and depositing proteins to their correct locations within cells. The research could eventually lead to novel treatments for diseases that result from flaws in protein delivery as well as the development of new types of antibiotics.

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