Caltech Biologists Spy on the Secret Inner Life of a Cell

The transportation of antibodies from a mother to her newborn child is vital for the development of that child's nascent immune system. Those antibodies, donated by transfer across the placenta before birth or via breast milk after birth, help shape a baby's response to foreign pathogens and may influence the later occurrence of autoimmune diseases. Images from biologists at the California Institute of Technology (Caltech) have revealed for the first time the complicated process by which these antibodies are shuttled from mother's milk, through her baby's gut, and into the bloodstream, and offer new insight into the mammalian immune system.

Caltech Scientists Engineer Supersensitive Receptor, Gain Better Understanding of Brain's Dopamine System

Genetically modifying a receptor found on the neurons that produce the neurotransmitter dopamine has given California Institute of Technology (Caltech) researchers a unique glimpse into the workings of the brain's dopamine system--as well as a new target for treating diseases that result from either too much or too little of this critical neurotransmitter.

Caltech Scientists Find Cells Coordinate Gene Activity with FM Bursts

How a cell achieves the coordinated control of a number of genes at the same time, a process that's necessary for it to regulate its own behavior and development, has long puzzled scientists. Michael Elowitz, an assistant professor of biology and applied physics at the California Institute of Technology (Caltech), along with Long Cai, a postdoctoral research scholar at Caltech, and graduate student Chiraj Dalal, have discovered a surprising answer. Just as human engineers control devices ranging from dimmer switches to retrorockets using pulsed--or frequency modulated (FM)--signals, cells tune the expression of groups of genes using discrete bursts of activation.

Bruce A. Hay, Caltech Biologist, Named NIH Pioneer Award Recipient

Bruce A. Hay, associate professor of biology at the California Institute of Technology (Caltech), has been named a 2008 NIH Director's Pioneer Award recipient by National Institutes of Health Director Elias A. Zerhouni, MD.

Scientists Find Our Eyes Evolved for 'X-Ray' Vision

The advantage of using two eyes to see the world around us has long been associated solely with our capacity to see in three dimensions. Now, a new study by scientists at Rensselaer Polytechnic Institute in New York and the California Institute of Technology (Caltech) has uncovered a truly eye-opening advantage to binocular vision: the ability to see through things.

Caltech Scientists Discover Why Flies Are So Hard to Swat

Over the past two decades, Michael Dickinson has been interviewed by reporters hundreds of times about his research on the biomechanics of insect flight. One question from the press has always dogged him: Why are flies so hard to swat?

Caltech Neurobiologists Discover Individuals Who "Hear" Movement

Individuals with synesthesia perceive the world in a different way from the rest of us. Because their senses are cross-activated, some synesthetes perceive numbers or letters as having colors or days of the week as possessing personalities, even as they function normally in the world. Now, researchers at the California Institute of Technology have discovered a type of synesthesia in which individuals hear sounds, such as tapping, beeping, or whirring, when they see things move or flash. Surprisingly, the scientists say, auditory synesthesia may not be unusual--and may simply represent an enhanced form of how the brain normally processes visual information.

Caltech Researchers Discover Dual-Use Sexual Attraction and Population-Control Chemicals in Nematodes

Organisms ranging from humans to plants to the lowliest bacterium use molecules to communicate. Some chemicals trigger the various stages of an organism's development, and still others are used to attract members of the opposite sex. Researchers at the California Institute of Technology have now found a rare kind of signaling molecule in the nematode worm Caenorhabditis elegans that serves a dual purpose, working as both a population-control mechanism and a sexual attractant.

A Viral Cloaking Device: Caltech biologists show how Human Cytomegalovirus hides from the immune system

Viruses achieve their definition of success when they can thrive without killing their host. Now, biologists Pamela Bjorkman and Zhiru Yang of the California Institute of Technology have uncovered how one such virus, prevalent in humans, evolved over time to hide from the immune system.

Protein Expert Joins Inaugural Class of Science Fellows:Caltech Vice Provost recognized with new Department of Defense award

The Department of Defense (DoD) named California Institute of Technology Vice Provost Stephen Mayo one of six university faculty scientists and engineers in the inaugural class of National Security Science and Engineering Faculty Fellows (NSSEFF). Up to $3 million of direct research support will be given to each NSSEFF fellow for up to five years. The grants are intended to engage the next generation of outstanding scientists and engineers in the most challenging technical issues facing the DoD.

Pages

Subscribe to RSS - BBE