Submitted by admin on Wed, 2012-02-29 08:00
Nearly all motile bacteria can sense and respond to their surroundings through a process called chemotaxis, which begins with proteins known as chemoreceptors. Now researchers at Caltech have built the first model that depicts precisely how chemoreceptors and the proteins around them are structured at the sensing tip of bacteria. Because chemotaxis plays a critical role in the first steps of bacterial infection, a better understanding of the process could pave the way for the development of new, more effective antibiotics.
Submitted by kfesenma on Mon, 2012-02-27 08:00
Bacteria have evolved different systems for secreting proteins. One, called a type VI secretion system, is found in about a quarter of all bacteria with two membranes. Despite being common, researchers have not understood how it works. Now a team, co-led by researchers at Caltech, has figured out the structure of the type VI secretion system apparatus and proposed how it might work—by shooting spring-loaded poison molecular daggers.
Submitted by katien on Wed, 2012-02-08 08:00
Our bodies are full of tiny superheroes—antibodies that fight foreign invaders, cells that regenerate, and structures that ensure our systems run smoothly. One such structure is myelin, a material that forms a protective cape around the axons of our nerve cells so that they can send signals quickly and efficiently. But myelin becomes damaged in demyelinating diseases like multiple sclerosis, leaving neurons without their sheaths. Researchers from Caltech now believe they have found a way to help the brain replace damaged myelin.
Submitted by admin on Tue, 2012-02-07 08:00
For their work in information and communication technologies, and biomedicine, Carver Mead, Moore Professor Emeritus of Engineering and Applied Science, and Alexander Varshavsky, Smits Professor of Cell Biology, have been honored by the BBVA Foundation as recipients of 2011 Frontiers of Knowledge awards.
Submitted by admin on Wed, 2012-01-25 08:00
Alexander Varshavsky, Caltech's Howard and Gwen Laurie Smits Professor of Cell Biology, has been awarded the 2012 King Faisal International Prize (KFIP) for Science. The winners of the prize, which also includes awards for medicine, Arabic language and literature, Islamic studies, and service to Islam, were announced in Riyadh, Saudi Arabia, on January 16.
Submitted by katien on Wed, 2012-01-25 08:00
A key feature of human and animal brains is that they are adaptive; they are able to change their structure and function based on input from the environment and on the potential associations, or consequences, of that input. To learn more about such neural adaptability, researchers at Caltech have explored the brains of insects and identified a mechanism by which the connections in their brain change to form new and specific memories of smells.
Submitted by katien on Thu, 2012-01-12 08:00
Scientists have long seen evidence of social behavior among many species of animals. Dolphins frolic together, lions live in packs, and hornets construct nests that can house a large number of the insects. And, right under our feet, it appears that roundworms are having their own little gatherings in the soil. Until recently, it was unknown how the worms communicate to one another when it's time to come together. Now, however, researchers from Caltech have identified, for the first time, the chemical signals that promote aggregation.
Submitted by lorio on Wed, 2011-12-07 08:00
Eric Davidson, Caltech's Norman Chandler Professor of Cell Biology, has been awarded the 2011 International Prize for Biology by the Japan Society for the Promotion of Science. On November 28, Davidson received a medal at a ceremony in Tokyo and an imperial gift, a silver vase from Emperor Akihito. The award also includes ten million yen (more than $125,000 USD).
Submitted by katien on Wed, 2011-11-30 08:00
Over the past year, researchers at Caltech, and around the world, have been studying a group of potent antibodies that have the ability to neutralize HIV in the lab; their hope is that they may learn how to create a vaccine that makes antibodies with similar properties. Now, biologists at Caltech led by Nobel Laureate David Baltimore have taken one step closer to that goal: they have developed a way to deliver these antibodies to mice and, in so doing, have effectively protected them from HIV infection.
Submitted by kfesenma on Wed, 2011-11-23 08:00
Although many mental illnesses are uniquely human, animals sometimes exhibit abnormal behaviors similar to those seen in humans with psychological disorders. Such behaviors are called endophenotypes. Now, Caltech researchers have found that mice lacking a gene that encodes a particular protein found in the synapses of the brain display a number of endophenotypes associated with schizophrenia and autism spectrum disorders.