The human body is full of tiny microorganisms, and the GI tract is home to the largest concentration and highest diversity of bacterial species. But how do these organisms persist and thrive in a system that is constantly in flux due to foods and fluids moving through it? A team led by Caltech biologist Sarkis Mazmanian believes it has found the answer, at least in one common group of bacteria: a set of genes that promotes stable microbial colonization of the gut.
The Rosen Center supports bioengineering research through the funding of fellows and faculty from many disciplines, including applied physics, chemical engineering, synthetic biology, and computer science.
A team of researchers led by newly arrived Caltech biologist Mitchell Guttman and Kathrin Plath of UCLA, has figured out how some RNA molecules take advantage of their position within the 3-D structure of genomic material to home in on targets.
Researchers have used a well-known, noninvasive technique to electrically stimulate a specific region deep inside the brain, causing volunteers to judge faces as more attractive than before their brains were stimulated.
A team of researchers led by biologists at Caltech has found that, in mouse models, the molecule microRNA-146a (miR-146a) acts as a critical regulator and protector of blood-forming stem cells during chronic inflammation, suggesting that a deficiency of miR-146a may be one important cause of blood cancers and bone marrow failure.
Los Angeles has had bouts of smog since the turn of the 20th century. Angelenos might now be living in a state of perpetual midnight—assuming we could live here at all—were it not for the work of Caltech professor Arie Jan Haagen-Smit.