09/08/2011 16:00:00
Kimm Fesenmaier

Caltech researchers have obtained the first high-resolution, three-dimensional images of a cell with a nucleus undergoing cell division. The observations, made using a powerful imaging technique in combination with a new method for slicing cell samples, indicate that one of the characteristic steps of mitosis is significantly different in some cells.

 

09/01/2011 16:00:00
Kimm Fesenmaier

Bacteria can generally be divided into two classes: those with just one membrane and those with two. Now researchers at the California Institute of Technology (Caltech) have used a powerful imaging technique to find what they believe may be the missing link between the two classes, as well as a plausible explanation for how the outer membrane may have arisen.

08/16/2011 07:00:00
Katie Neith

Much like cities organize contingency plans and supplies for emergencies, chronic infectious diseases like HIV form reservoirs that ensure their survival in adverse conditions. But these reservoirs—small populations of viruses or bacteria of a specific type that persist despite attack by the immune system or drug treatment—are not always well understood. Now, however, researchers at Caltech believe they have begun to decode how a reservoir of infection can persist in HIV-positive populations.

08/02/2011 07:00:00
Katie Neith

Lea Goentoro remembers the precise moment that biology made an impression on her. It was 2002 and she was a PhD candidate in chemical engineering at Princeton. During a presentation, developmental biologist and Nobel laureate Eric Wieschaus showed a movie of a live fly embryo under a microscope that was undergoing gastrulation, a process she found fascinating. Now, nine years after that fateful day in New Jersey, Goentoro is Caltech's newest faculty member in the Division of Biology. 

07/29/2011 07:00:00
Kimm Fesenmaier

When it comes to a small HIV-fighting protein, called cyanovirin-N, Caltech researchers have found that two are better than one.

07/25/2011 07:00:00
Katie Neith

For modern biologists, the ability to capture high-quality, 3D images of living tissues or organisms over time is necessary to answer problems in areas ranging from genomics to neurobiology and developmental biology. Looking to improve upon current methods of imaging, researchers from Caltech have developed a novel approach that could redefine optical imaging of live biological samples by simultaneously achieving high resolution, high penetration depth, and high imaging speed.

 

07/17/2011 07:00:00
Katie Neith

Each time a virus invades a healthy individual, antibodies created by the body fight to fend off the intruders. For HIV, the antibodies are very specific and are generated too slowly to combat the rapidly changing virus. However, scientists have found that some HIV-positive people develop highly potent antibodies that can neutralize different subtypes of the virus. Now, a study involving Caltech researchers points to the possibility of using these neutralizing antibodies in the development of a vaccine.

 

07/05/2011 07:00:00
Lori Oliwenstein

Figuring a virus's host is can be difficult, especially when you're talking about bacteriophages, a group of bacteria-infecting viruses. The problem lies in identifying which bacteriophages are infecting which bacteria, without having to culture either the viruses or their hosts in the lab. Now, a Caltech-led team has created a technique that can "physically link single bacterial cells harvested from a natural environment with a viral marker genes," the scientists report in the July 1 issue of the journal Science.

06/22/2011 06:00:00
Michael Rogers

As part of a program to foster innovative biomedical research projects, an anonymous donor has pledged $3 million each to Caltech and City of Hope to strengthen scientific collaborations between the two leading research institutions.

06/16/2011 10:00:00
Kathy Svitil

Elliot Meyerowitz, a plant genetics and developmental biology expert at Caltech, has been awarded one of 15 five-year, $5 million grants for fundamental plant science research from the Howard Hughes Medical Institute and the Gordon and Betty Moore Foundation. Meyerowitz is an expert in the study of Arabidopsis thaliana, a small flowering plant in the mustard family and a model organism for plant genetics and molecular biology studies.

 

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