Medical Science News

09/18/2014 09:24:46
Kimm Fesenmaier
Researchers around the country are adopting a technique developed in the Caltech lab of Nobel Laureate David Baltimore to try to guard against infection. The method, called VIP, was originally designed to trigger an immune response to HIV, and because of its success with HIV is now being studied, in mice, for protection against influenza, malaria, hepatitis C, and tuberculosis.
09/06/2011 07:00:00
Kimm Fesenmaier

Caltech senior Wilson Ho spent his summer completing a SURF project in the lab of Robert Grubbs, one of the winners of the 2005 Nobel Prize in Chemistry. Ho tells his nonscientist friends and family that the goal of his project is to develop "stem-cell Band-Aids" that might one day help restore vision in those suffering from macular degeneration.

08/16/2011 07:00:00
Katie Neith

Much like cities organize contingency plans and supplies for emergencies, chronic infectious diseases like HIV form reservoirs that ensure their survival in adverse conditions. But these reservoirs—small populations of viruses or bacteria of a specific type that persist despite attack by the immune system or drug treatment—are not always well understood. Now, however, researchers at Caltech believe they have begun to decode how a reservoir of infection can persist in HIV-positive populations.

08/08/2011 07:00:00
Kimm Fesenmaier

One looks like little more than a stethoscope head attached to a wire; the other seems to be an oven mitt with three metal disks sewn on. Simple, yes, but these prototype medical devices—developed by young Caltech researchers working on a SURF project—could one day save lives.

07/29/2011 07:00:00
Kimm Fesenmaier

When it comes to a small HIV-fighting protein, called cyanovirin-N, Caltech researchers have found that two are better than one.

07/21/2011 07:00:00
Lori Oliwenstein

Zcube Srl, a research venture of the Italian pharmaceutical company Zambon, and Caltech have signed an exclusive research and option agreement to develop and commercialize skin patches that contain embedded carbon nanotubes for delivering drugs.

07/17/2011 07:00:00
Katie Neith

Each time a virus invades a healthy individual, antibodies created by the body fight to fend off the intruders. For HIV, the antibodies are very specific and are generated too slowly to combat the rapidly changing virus. However, scientists have found that some HIV-positive people develop highly potent antibodies that can neutralize different subtypes of the virus. Now, a study involving Caltech researchers points to the possibility of using these neutralizing antibodies in the development of a vaccine.

 

07/05/2011 07:00:00
Lori Oliwenstein

Figuring a virus's host is can be difficult, especially when you're talking about bacteriophages, a group of bacteria-infecting viruses. The problem lies in identifying which bacteriophages are infecting which bacteria, without having to culture either the viruses or their hosts in the lab. Now, a Caltech-led team has created a technique that can "physically link single bacterial cells harvested from a natural environment with a viral marker genes," the scientists report in the July 1 issue of the journal Science.

06/22/2011 06:00:00
Michael Rogers

As part of a program to foster innovative biomedical research projects, an anonymous donor has pledged $3 million each to Caltech and City of Hope to strengthen scientific collaborations between the two leading research institutions.

05/24/2011 07:00:00
Katie Neith

There's a wealth of health information hiding in the human immune system. Accessing it, however, can be very challenging, as the many and complex roles that the immune system plays can mask the critical information that is relevant to addressing specific health issues. Now, research led by scientists from the California Institute of Technology (Caltech) has shown that a new generation of microchips developed by the team can quickly and inexpensively assess immune function.

05/19/2011 14:30:00
Kathy Svitil

A team of researchers from the University of California, Los Angeles (UCLA), Caltech, and the University of Louisville have used a stimulating electrode array to assist a paralyzed man to stand, step on a treadmill with assistance, and, over time, to regain voluntary movements of his limbs. The electrical signals provided by the array, the researchers have found, stimulate the spinal cord's own neural network so that it can use the sensory input derived from the legs to direct muscle and joint movements.

 

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