The Grand Challenges in Global Health initiative, a major effort to achieve scientific breakthroughs against diseases that kill millions of people each year in the world's poorest countries, today offered 43 grants totaling $436.6 million for a broad range of innovative research projects involving scientists in 33 countries, including David Baltimore, president of the California Institute of Technology. The ultimate goal of the initiative is to create "deliverable technologies"--health tools that are not only effective, but also inexpensive to produce, easy to distribute, and simple to use in developing countries.