News articles tagged with "HIV"

03/27/2015 08:49:26
Douglas Smith
Finding an anti-AIDS vaccine remains an elusive goal—partly because the HIV virus quickly mutates to evade the vaccine's antibodies. In a Watson Lecture on April 1, Caltech's Pamela J. Bjorkman will describe ways to neutralize that mutational advantage.
01/29/2015 09:23:04
Kimm Fesenmaier
Caltech researchers have developed antibody-based molecules that are hundreds of times better than our natural defenses at binding to and neutralizing the HIV virus.
09/18/2014 09:24:46
Kimm Fesenmaier
Researchers around the country are adopting a technique developed in the Caltech lab of Nobel Laureate David Baltimore to try to guard against infection. The method, called VIP, was originally designed to trigger an immune response to HIV.
02/09/2014 10:05:05
Kimm Fesenmaier
"The method that we developed has now been validated in the most natural possible setting in a mouse," says David Baltimore, president emeritus and the Robert Andrews Millikan Professor of Biology at Caltech.
01/30/2014 14:02:45
Katie Neith
Researchers at Caltech are the first to have utilized high-resolution electron microscopy to look at HIV infection within the actual tissue of an infected organism, providing perhaps the most detailed characterization yet of HIV infection in the gut.
11/15/2013 11:02:14
Caltech researchers have demonstrated a method for using a lab-on-a-chip device and a cell phone to determine a concentration of molecules, such as HIV RNA molecules, in a sample.
10/08/2012 16:28:37
Katie Neith
Years spent studying HIV in the lab were beginning to make Pamela Bjorkman feel disconnected from the possible impact of her work. So this summer she visited India, spending time with HIV-positive women and others who are at risk.
12/08/2011 08:00:00
Kimm Fesenmaier

Rustem Ismagilov, the new John W. and Herberta M. Miles Professor of Chemistry and Chemical Engineering at Caltech, believes in the ability of science and technology to address significant societal problems—from the spread of HIV and drug resistance to bacterial imbalances in the gut.

11/30/2011 08:00:00
Katie Neith

Over the past year, researchers at Caltech, and around the world, have been studying a group of potent antibodies that have the ability to neutralize HIV in the lab; their hope is that they may learn how to create a vaccine that makes antibodies with similar properties. Now, biologists at Caltech led by Nobel Laureate David Baltimore have taken one step closer to that goal: they have developed a way to deliver these antibodies to mice and, in so doing, have effectively protected them from HIV infection.


10/27/2011 18:00:00
Katie Neith

Using highly potent antibodies isolated from HIV-positive people, researchers have recently begun to identify ways to broadly neutralize the many possible subtypes of HIV. Now, a team led by biologists at Caltech has built upon one of these naturally occurring antibodies to create a stronger version they believe is a better candidate for clinical applications. 


08/16/2011 07:00:00
Katie Neith

Much like cities organize contingency plans and supplies for emergencies, chronic infectious diseases like HIV form reservoirs that ensure their survival in adverse conditions. But these reservoirs—small populations of viruses or bacteria of a specific type that persist despite attack by the immune system or drug treatment—are not always well understood. Now, however, researchers at Caltech believe they have begun to decode how a reservoir of infection can persist in HIV-positive populations.

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