04/14/2016 11:22:01
Marcus Woo
Researchers at Caltech and their colleagues have identified how at least one brain cancer adapts quickly to therapeutic drugs—and they show that by formulating the right combination of drugs, doctors could potentially overcome this resistance and stop a tumor in its tracks.
08/23/2012 18:00:00
Kimm Fesenmaier

Caltech researchers have shown for the first time that a specific sugar, known as GlcNAc ("glick-nack"), plays a key role in helping cancer cells grow rapdily and survive under harsh conditions. The finding suggests new potential targets for therapeutic intervention. 

07/12/2012 07:00:00
Michael Rogers

. Now, an endowment established by the Raymond and Beverly Sackler Foundation will strengthen the Caltech-UCLA partnership and advance the Baltimore lab’s interdisciplinary research into areas where mathematics and engineering converge with biology.

06/26/2012 15:00:00
Marcus Woo
Imagine if doctors could perform surgery without ever having to cut through your skin. Or if they could diagnose cancer by seeing tumors inside the body with a procedure that is as simple as an ultrasound. Thanks to a technique developed by engineers at Caltech, all of that may be possible in the not-so-distant future.
02/29/2012 08:00:00
Kimm Fesenmaier

Nearly all motile bacteria can sense and respond to their surroundings through a process called chemotaxis, which begins with proteins known as chemoreceptors. Now researchers at Caltech have built the first model that depicts precisely how chemoreceptors and the proteins around them are structured at the sensing tip of bacteria. Because chemotaxis plays a critical role in the first steps of bacterial infection, a better understanding of the process could pave the way for the development of new, more effective antibiotics.

06/22/2011 06:00:00
Michael Rogers

As part of a program to foster innovative biomedical research projects, an anonymous donor has pledged $3 million each to Caltech and City of Hope to strengthen scientific collaborations between the two leading research institutions.

05/24/2011 07:00:00
Katie Neith

There's a wealth of health information hiding in the human immune system. Accessing it, however, can be very challenging, as the many and complex roles that the immune system plays can mask the critical information that is relevant to addressing specific health issues. Now, research led by scientists from the California Institute of Technology (Caltech) has shown that a new generation of microchips developed by the team can quickly and inexpensively assess immune function.

01/13/2011 08:00:00
Marcus Woo

More than 50 years ago, at a meeting of the American Physical Society hosted by Caltech, Richard Feynman gave a talk called “There’s Plenty of Room at the Bottom.” In his visionary speech, Feynman discussed the technological promise of tiny machines as small as a few atoms. This promise has grown into a full-fledged discipline we now know as nanoscience, and it is the subject of TEDxCaltech’s last session, “Nanoscience and Future Biology.”

08/04/2010 17:00:00
Kathy Svitil

One key to fighting diseases such as leukemia and anemia is gaining an understanding of the genes and molecules that control the function of hematopoietic—or blood—stem cells, which provide the body with a constant supply of red and white blood cells and platelets. Biologists at Caltech have taken a large step toward that end, with the discovery of a novel group of molecules that are found in high concentrations within hematopoietic stem cells and appear to regulate their production.

07/02/2010 02:00:00
Kathy Svitil

When does a cell decide its particular identity? According to Caltech biologists, in the case of T cells—immune system cells that help destroy invading pathogens—the answer is when the cells begin expressing a particular gene called Bcl11b.

05/12/2010 17:00:00
Kathy Svitil

A team of scientists from Columbia University, Arizona State University, the University of Michigan, and Caltech have programmed an autonomous molecular "robot" made out of DNA to start, move, turn, and stop while following a DNA track.

The development could ultimately lead to molecular systems that might one day be used for medical therapeutic devices and molecular-scale reconfigurable robots—robots made of many simple units that can reposition or even rebuild themselves to accomplish different tasks.

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