Friday, March 29, 2013
"Nanoscale construction with DNA"
Shawn Douglas, Assistant Professor , Department of Cellular and Molecular Pharmacology, University of California San Francisco
This is a Special Bioengineering Seminar.
Abstract: The programmability of DNA makes it an attractive material for constructing intricate nanoscale shapes. One method for creating these structures is DNA origami, in which a multiple-kilobase single-stranded 'scaffold' is folded into a custom nanoscale shape by interacting with hundreds of short oligonucleotide 'staple' strands. I will talk about our efforts to realize demand-meeting applications of this method, including our recent development of nanoscale devices to mimic cell-signaling stimulation carried out by our own immune systems.